Mespilus germanica Flavonoids Attenuate Cognitive Dysfunction in the Streptozotocin-induced Rat Model of Alzheimer's Disease
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منابع مشابه
Mespilus germanica leaves flavonoids improve passive avoidance memory and apoptosis in a rat model of amyloid-β neurotoxicity
Introduction: Alzheimer’s disease (AD) is a common progressive, neurodegenerative disorder with no preventive or curative therapy until now. Use of natural products as an important source of neuroprotective flavonoids against AD has been considered recently. In this study, the effect of Mespilus germanica leaves (MGL) flavonoids treatment on memory dysfunction and apoptosis in the amyloid beta ...
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Introduction: Olibanum improves memory in different models of learning. However, the effect of olibanum on models of Alzheimer’s disease has been less studied. In the present study, the effect of olibanum on memory in normal rats and in a rat model of Alzheimer disease induced by intracerebroventricular injections of streptozotocin was evaluated. Methods: Rats received an aqueous extract of...
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PURPOSE Alzheimer's disease (AD) results in memory impairment and neuronal cell death in the brain. Previous studies demonstrated that intracerebroventricular administration of streptozotocin (STZ) induces pathological and behavioral alterations similar to those observed in AD. Agmatine (Agm) has been shown to exert neuroprotective effects in central nervous system disorders. In this study, we ...
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متن کاملAssessing The Effect of Hydro-alcoholic Leaf Extract of Mespilus germanica on the Blood levels of Glucose and Lipids in Streptozotocin Induced Diabetic Male Rats
Background & Objective: Diabetes Mellitus is an abnormality in carbohydrate, lipid and protein metabolism that can lead to hyperglycemia and hyperlipidemia. This study aimed at assessing the effect of hydro-alcoholic leaf extract of Mespilus germanica on the blood levels of glucose and lipids in diabetic male rats. Materials & Methods: In this experimental study 48 adult male rats were rando...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Sciences
سال: 2018
ISSN: 0250-474X
DOI: 10.4172/pharmaceutical-sciences.1000406